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    Exploding Head Syndrome: Symptoms, Causes, and Treatment

    Because exploding head syndrome is such a rare condition and episodes are hard to predict, there are no formal treatment guidelines.

    Older suggested that reassuring someone that the condition isn’t life threatening can reduce their likelihood of experiencing more episodes.

    If an underlying condition such as sleep paralysis or chronic migraine is suspected as the cause, addressing that condition directly could also bring some relief.

    If these strategies don’t offer the expected results, anecdotal reports indicate that some health professionals may also include the like:

    • Clomipramine: a tricyclic antidepressant typically used to treat obsessive-compulsive disorder (OCD)
    • Amitriptyline: another tricyclic antidepressant used to treat major depressive disorder
    • Topiramate: an anticonvulsant prescribed to treat seizures
    • Duloxetine hydrochloride: an antidepressant
    • Nifedipine: an antihypertensive drug used to treat high blood pressure

    Some also suggest that single-pulse transcranial magnetic stimulati

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